Cryptsetup with LUKS is a very useful tool, unfortunately there is only one GUI tool for managing crypto devices. It is called GDECrypt. It is good tool, but needs a little design improvements.
My proposal is to call it CryptoDisk Manager (luks-manager) and to design it by following the below described specifications. Since TrueCrypt has his own GUI (which is very nice), my proposal is to drop TrueCrypt support from this new application completely and focus only on LUKS encrypted devices.
Displays all mounted crypto devices (including container files). For each mounted crypto device displays:
Big icons from the left:
Menu: